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20, AVENUE APPIA – CH-1211 GENEVA 27 – SWITZERLAND – TEL CENTRAL +41 22 791 2111 – FAX CENTRAL +41 22 791 3111 – WWW.WHO.INT Ref.: C.L.27.2022 The World Health Organization (WHO) presents its compliments to Member States and Associate Members and has the pleasure of announcing that the 45th Expert Committee on Drug Dependence (ECDD) will meet from 10 to 14 October 2022 in Geneva, Switzerland. Given that WHO expert committee meetings are of a closed nature, this letter serves to notify Member ... States of the substances under review at the 45th ECDD, which are in the Annex I file, attached for reference. WHO is mandated by the 1961 and 1971 International Drug Control Conventions to make recommendations to the UN Secretary-General on the need for and level of international control of psychoactive substances based on the advice of its independent scientific advisory body, the ECDD. To assess whether or not a psychoactive substance should be placed under international control, the ECDD convenes annually to review the potential of this substance to cause dependence, abuse and harm to health, as well as any therapeutic applications. In order to perform this review and make evidence-based decisions, the ECDD conducts medical, scientific, and public health evaluations of the selected psychoactive substances using the best available information. Although the meetings are of a closed nature, Member States are invited to contribute to the ECDD review process by joining the 45th ECDD Information Session on 10 October 2022. The Information Session will be held virtually and allow interested parties to learn about present and future activities of the ECDD Secretariat, and to present information concerning substances under review to the Expert Committee for consideration in its deliberations. Registration information will be made available on the ECDD web site in due course: https://www.who.int/medicines/access/controlled-substances/en/. As in the past and in line with the publication “Guidance on the WHO review of psychoactive substances for international control” (EB126/2010/REC1, Annex 6),1 Member States can also contribute to the ECDD review process by providing up to date and accurate information concerning the substances under review in advance of the meeting. For this purpose, and as per previous practice, a questionnaire will be sent to Member States to gather country information on the legitimate use, harmful use, status of national control and potential impact of international control for each substance under evaluation. 1 https://apps.who.int/gb/ebwha/pdf_files/EB126-REC1/B126_REC1-en.pdf#page=90 ... ENCLS.: (2)  Page 2 C.L.27.2022 ... Annex II to this Circular Letter contains a list of national focal points officially designated by Member States in previous years who provide country information to the ECDD through the Member States questionnaire referred to above. If the focal point information requires changes or amendments, Member States are invited to inform the WHO ECDD Secretariat by email to [email protected] by 30 June 2022 with the subject “45ECDD Focal Point: (Country Name)”. If the individual(s) on the list is(are) still the official focal point(s) for completing the ECDD Member State questionnaire this year and if no additions or amendments to focal point(s) details are made by 30 June 2022, the focal point(s) from the list will be given further instructions and direct access to online questionnaires by the WHO Secretariat. Results of the questionnaires will be prepared as a report as part of the 45th ECDD substance review process. In addition to the questionnaire, Member States are also encouraged to provide any additional relevant information (unpublished or published) on substances to be reviewed by the 45th ECDD by emailing [email protected] with the subject “Ref: C.L.27.2022”. The World Health Organization takes this opportunity to renew to Member States and Associate Members the assurance of its highest consideration. GENEVA, 17 June 2022 Annex I 45th Expert Committee on Drug Dependence (ECDD) Substances for review 10-14 October 2022 Critical reviews: The substances listed below have never been formally reviewed by WHO and are not currently under international control. Information was brought to WHO’s attention that these substances are clandestinely manufactured, of especially serious risk to public health and society, and of no recognised therapeutic use by any Party. The Expert Committee will consider whether information presented during a critical review may justify the scheduling or a change in the scheduling of the substance in the 1961 or 1971 Conventions. Synthetic cannabinoid receptor agonist 1. ADB-BUTINACA (ADB-BINACA) Benzodiazepines 2. Adinazolam 3. Bromazolam Novel synthetic opioids 4. Protonitazene (propoxynitazene) 5. Etazene (etodesnitazene) 6. Etonitazepyne (N-pyrrolidino etonitazene) 7. 2-Methyl-AP-237 Cathinones/stimulants 8. alpha-PiHP 9. 3-Methylmethcathinone (3-MMC) Pre-reviews: The substances listed below have been proposed for a pre-review. The purpose of a pre-review is to determine whether current information justifies an Expert Committee critical review. A pre-review is a preliminary analysis and findings at this stage should not determine whether the control status of a substance should be changed. Medicines 1. Zopiclone  Annex 2 List of focal points by Member States in previous years Country Name Focal Point Email Afghanistan Shahpoor Yousuf [email protected] Albania Linda Ternova [email protected] Algeria Ghrieb Houria [email protected] Andorra Carla Lobaco Valls [email protected] Andorra Carme Pallarés Papaseit [email protected] Angola Antigua and Barbuda Argentina G. Rebaldería [email protected] Armenia Hasmik Martirosyan [email protected] Australia Sarah Ferguson [email protected] Australia Agastya Bharadwaj [email protected] Austria Raphael Bayer [email protected] Azerbaijan Telman Suleyman Oglu Mammadhassanov [email protected] Bahamas Bahrain Samar Yousef Salem [email protected] Bangladesh Habibur Rahman Khan [email protected] Barbados Maryam Hinds [email protected] Belarus Aleksey Kralko [email protected] Belgium Lies Gremeaux [email protected] Belize Benin Hope Akohouvi Amou [email protected] Bhutan Dil Kumar Subba [email protected] 1  Annex 2 Country Name Focal Point Email Bolivia (Plurinational State of) Maria Julia Carrasco [email protected] Bosnia and Herzegovina Ana Cvijanović [email protected] Bosnia and Herzegovina Sabina Šahman [email protected] Botswana Vivian Sebako [email protected] Brazil Maria Dilma Alves Teodoro [email protected] Brazil [email protected] Brazil Renata de Morais Souza [email protected] Brazil [email protected] Brunei Darussalam Hajah Zanatul ‘Aini Haji Zainin (Ms) [email protected] Bulgaria Slaveyka Nikolova [email protected] Bulgaria Alexander Panayotov [email protected] Burkina Faso [email protected] Burundi Aimable Bizoza [email protected] Cabo Verde Fernanda Marques [email protected] Cambodia Chhit Sophal [email protected] Cameroon Ketchozo Loko Wilfried [email protected] Canada [email protected] Central African Republic Chad Haoua Haroun Saker [email protected] Chile Javiera Erazo Leiva [email protected] China [email protected] China Wang Wei [email protected] China [email protected] 2  Annex 2 Country Name Focal Point Email Colombia Oscar Ricardo Santana [email protected] Colombia [email protected] Colombia A. Peñuela [email protected] Comoros Congo Ghislaine Mbelu Kanyunya [email protected] Cook Islands Valentino Wichman [email protected] Costa Rica Marchena Vasquez [email protected] Côte d'Ivoire Ernest Zotoua [email protected] Croatia Romana Katalinić [email protected] Cuba Cyprus John Kkolos [email protected] Czechia Vlastimil Brandejs [email protected] Democratic People's Republic of Korea Kim Jong Guk Democratic Republic of the Congo Denmark Kari Gragaasen [email protected] Djibouti Dominica Dominican Republic Elizabeth Ruiz [email protected] Dominican Republic Francisca Dalia Castillo Sanchez [email protected] Ecuador Enríquez Anaya [email protected] Ecuador Rojeab Bravo [email protected] Egypt Nahla Attia [email protected] El Salvador José Mauricio Bermúdez Recinos [email protected] 3  Annex 2 Country Name Focal Point Email Equatorial Guinea Eritrea Michael Girmay Haile [email protected] Estonia Malle Tiidelepp [email protected] Estonia Katrin Tomson-Johanson [email protected] Eswatini Ethiopia Baharu Zewdie Moya [email protected] Fiji Apolosi Vosanibola [email protected] Finland Katja Pihlainen [email protected] France Aldine Fabreguettes [email protected] Gabon Okouyi Ndakissa [email protected] Gambia Georgia Ketevan Gorozia [email protected] Germany Elke Lehmann [email protected] Ghana Martha Gyansa-Lutterodt [email protected] Greece Ioanna Siamou [email protected] Grenada Guatemala Erica Janeth Cohobon Lepe [email protected] Guinea Guinea-Bissau Guyana Haiti Marie Judith Robuste Roche [email protected] Honduras Alex Virgilio Santos Moreno [email protected] Hungary Tímea Kahlesz [email protected] 4  Annex 2 Country Name Focal Point Email Iceland Bjarni Sigurðsson [email protected] India Rakesh Chadda [email protected] Indonesia Agusdini Banun Saptaningsih [email protected] Iran (Islamic Republic of) Abdehzadeh [email protected] Iran (Islamic Republic of) Alebouyeh [email protected] Iran (Islamic Republic of) Ahmad Hajebi [email protected] Iraq Abdulghani [email protected] Ireland Brennan [email protected] Ireland Byran Sheehan [email protected] Israel Itamar Grotto [email protected] Israel Tal Lavy [email protected] Israel [email protected] Italy Pietro Canuzzi [email protected] Itay Rocco Signorile [email protected] Jamaica Lishann Salmon [email protected] Jamaica Winston De La Haye [email protected] Jamaica Michelle Walker [email protected] Japan [email protected] Jordan Heyam Wahbeh [email protected] Kazakhstan Prilutskaya Marina [email protected] Kenya Anthony Toroitich [email protected] Kenya Simon Njuguna [email protected] Kiribati Biribo Kararaiti [email protected] 5  Annex 2 Country Name Focal Point Email Kuwait Ali Abdulmohsen Jaragh [email protected] Kyrgyzstan Kanyshai Damirbek [email protected] Lao People's Democratic Republic Khatthanaphone Phandoangsy [email protected] Latvia Linda Veisberga [email protected] Lebanon Marie-Therese Matar [email protected] Lesotho Masello Sello [email protected] Liberia Libya Lithuania Rima Mačiūnienė [email protected] Luxembourg Alain Origer [email protected] Madagascar Mahavany Vénot Amélie Nicole [email protected] Malawi Michael Udedi [email protected] Malaysia Rohaida Binti Zakaria [email protected] Maldives Aishath Mohamed [email protected] Mali Mahamadou Ousmane Maiga [email protected] Malta Victor P. Pace [email protected] Marshall Islands Julia Alfred [email protected] Mauritania Hamoud Fadel Yamohomed [email protected] Mauritius [email protected] Mauritius A. Jhugroo [email protected] Mexico David Correa Pina [email protected] Micronesia (Federated States of) Benido Victor [email protected] Monaco Isabelle Kessedjian [email protected] 6  Annex 2 Country Name Focal Point Email Mongolia Luvsandagva Purevdorj [email protected] Montenegro Jasna Sekulic [email protected] Morocco Hassan Elkarimi [email protected] Morocco Jallal Toufiq [email protected] Mozambique Eugénia Guelfrida Salesio Teodoro [email protected] Myanmar Nanda Myo Aung Wan [email protected] Myanmar Tin Wah Wah Win [email protected] Namibia Ester Mvula [email protected] Nauru Richard Leona [email protected] Nepal Netherlands Liefke Huizinga [email protected] New Zealand Emily Kay [email protected] New Zealand Lauren Bellamore [email protected] Nicaragua Karla Vanessa Delgado Martinez [email protected] Niger Haoua Na Allah Alou [email protected] Nigeria Rafiu Akanbi Folarin [email protected] Niue Grizelda Mokoia [email protected] North Macedonia Norway Anne S. Onsgård Sagabråten [email protected] Oman Mahmood Al Abri [email protected] Pakistan Rizwan Taj [email protected] Palau [email protected] Palau [email protected] 7  Annex 2 Country Name Focal Point Email Palau Marla Ito [email protected] Panama Papua New Guinea Vicky Wari [email protected] Paraguay Peru Judith Castañeda Alcántara [email protected] Philippines Ivanhoe Escartin [email protected] Poland Michał Kidawa [email protected] Portugal Graça Vilar [email protected] Puerto Rico Qatar Majid Ali Al Abdulla [email protected] Republic of Korea Hyun Jun Kim [email protected] Republic of Moldova Stanislav Grosu [email protected] Romania Camelia Bunaciu [email protected] Russian Federation Olga Panova [email protected] Rwanda Saint Kitts and Nevis Saint Lucia Donna Daniel [email protected] Saint Lucia Paul Caleb [email protected] Saint Vincent and the Grenadines Samoa Robert Thomsen [email protected] San Marino Claudio Muccioli [email protected] Sao Tome and Principe Saudi Arabia Adnan Alshammary [email protected] 8  Annex 2 Country Name Focal Point Email Senegal Bintou Dia [email protected] Serbia Nataša Savić [email protected] Seychelles Sierra Leone Singapore Ong Lay Tin [email protected] Slovakia Jan Lehotsky [email protected] Slovenia Joze Hren [email protected] Solomon Islands Paul Orotaloa [email protected] Solomon Islands Stephen Araitewa [email protected] Somalia South Africa MG Molewa [email protected] South Sudan Spain Manuel Ibarra [email protected] Spain Lidia Fernandez Matellano [email protected] Sri Lanka [email protected] S.C. Wickramasinghe Sudan Suriname Sweden David Lorentzon [email protected] Switzerland Diane Steber [email protected] Syrian Arab Republic Ahmed Al-Salama [email protected] Tajikistan Salim Abdulazizov [email protected] Thailand Chantharakul [email protected] Thailand Chavanich [email protected] 9  Annex 2 Country Name Focal Point Email Thailand Tontisirin [email protected] Timor-Leste Soares Henriques [email protected] Togo Mouhoudine Yerima [email protected] Tokelau Tonga Melenaite Mahe [email protected] Trinidad and Tobago Rohit Doon [email protected] Tunisia Türkiye Demet Aydınkarahaliloğlu [email protected] Turkmenistan Tuvalu Uganda Hafsa Lukwata [email protected] Ukraine Liudmyla Konoshevych [email protected] Ukraine Viktoria Kurlova [email protected] Ukraine Sergii Shum [email protected] United Arab Emirates United Kingdom of Great Britain and Northern Catherine Crawford [email protected] Ireland United Kingdom of Great Britain and Northern Martin White [email protected] Ireland United Republic of Tanzania Sara Maongezi [email protected] United States of America Jim Hunter [email protected] Uruguay Horacio Porciuncula [email protected] Uzbekistan Vanuatu Jerry Iaruel [email protected] 10  Annex 2 Country Name Focal Point Email Venezuela (Bolivarian Republic of) Viet Nam Mhin Tam Nguyen [email protected] Yemen Zambia Nita Besa [email protected] Zimbabwe Eneti Siyame [email protected] = = = 11 Saatja: <[email protected]> Saadetud: 20.06.2022 17:37 Koopia: <[email protected]> Teema: WHO: C.L.27.2022 (45th ECDD) Dear Member States of the World Health Organization,Please find attached, in the six official languages, C.L.27.2022 regarding the 45th Expert Committee on Drug Dependence (ECDD) which will be held from 10 to 14 October 2022 in Geneva, Switzerland.Should you have questions regarding C.L.27.2022 please send an email to [email protected] regards,Department of Governing BodiesWorld Health Organization***DO NOT REPLY TO THIS E-MAIL. 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